Critical Appraisal of Research in Evidence-Based Practice or EBP
he Assignment (Evidence-Based Project) Part 3A: Critical Appraisal of Research Conduct a critical appraisal of the four peer-reviewed articles you selected by completing the Evaluation Table within the Critical Appraisal Tool Worksheet Template. Choose a total of four peer- reviewed articles that you selected related to your clinical topic of interest in Module 2 and Module 3. Note: You can choose any combination of articles from Modules 2 and 3 for your Critical Appraisal. For example, you may choose two unfiltered research articles from Module 2 and two filtered research articles (systematic reviews) from Module 3 or one article from Module 2 and three articles from Module 3. You can choose any combination of articles from the prior Module Assignments as long as both modules and types of studies are represented. Part 3B: Critical Appraisal of Research Based on your appraisal, in a 1-2-page critical appraisal, suggest a best practice that emerges from the research you reviewed. Briefly explain the best practice, justifying your proposal with APA citations of the research. Critical Appraisal of Research in Evidence-Based Practice or EBP.
ORDER A PLAGIARISM -FREE PAPER NOW
Part A: Critical Appraisal of Research (Matrix)
Full APA formatted citation of selected article. | Article #1 | Article #2 | Article #3 | Article #4 |
Andriani, Y., & Nadjib, M. (2018). The importance of implementation of hand hygiene practice in reducing healthcare-associated infections: A systematic review. The 2nd International Conference on Hospital Administration (KnE Life Sciences),135–145. https://doi.org/10.18502/kls.v4i9.3565
|
Borren, N.Z., Ghadermarzi, S., Hutfless, S., & Ananthakrishnan, A.N. (2017). The emergence of Clostridium difficile infection in Asia: A systematic review and meta-analysis of incidence and impact. PLOS ONE, 12(5), 1-16. https:// doi.org/10.1371/journal.pone.0176797
|
Freeman, M.C., Stocks, M.E., Cumming, O., Jeandron, A., Higgins, J.P.T., Wolf, J., Prüss-Ustün, A., Bonjour, S., Hunter, P.R., Fewtrell, L., & Curtis, V. (2014). Hygiene and health: Systematic review of handwashing practices worldwide and update of health effects. Tropical Medicine & International Health, 19(8), 906–916. https://doi.org/10.1111/tmi.12339 | Gerding, D.N., Muto, C.A., & Owens Jr, R.C. (2008). Measures to control and prevent Clostridium difficile infection. Clinical Infectious Diseases, 46(Supplement 1), S43-S49. http://dx.doi.org/10.1086/521861
|
|
Evidence Level *
(I, II, or III)
|
Level I | Level I | Level I | Level II |
Conceptual Framework
Describe the theoretical basis for the study (If there is not one mentioned in the article, say that here).** |
Implied: Washing hands with soap and water will effectively dislodge microbial particles by dissolving lipid bonds. Critical Appraisal of Research in Evidence-Based Practice or EBP.
|
Implied: Resistant strains of bacteria develop this ability after repeated exposures to antibiotics. | Implied: handwashing will reduce the population of microbes on the hands and reduce the chances of developing diarrheal diseases. | Implied: Clostridium difficile populations are high in hospital environments and the hands of healthcare employees. |
Design/Method
Describe the design and how the study was carried out (In detail, including inclusion/exclusion criteria). |
Systematic review with PRISMA method.
Article inclusion was publication within the last 10 years. |
Systematic review and meta-analysis.
Inclusion was publication in the last 10 years.
|
Systematic review | Quantitative study. |
Sample/Setting
The number and characteristics of patients, attrition rate, etc. |
Sample: n = 11 articles
Setting: Electronic database search |
Sample: n = 51 studies and 37,663 patients
Setting: Electronic databases |
Sample: n = 42 studies
Setting: Databases |
Sample: All admitted patients
Setting: The hospital |
Major Variables Studied
List and define dependent and independent variables |
Independent variable: Handwashing with soap and water.
Dependent variable: Infection with HAIs.
|
Independent variable: Antibiotic use.
Dependent variable: Development of resistant strains of CD. |
Independent variable: Handwashing
Dependent variable: Diarrheal diseases. |
Independent variable: Handwashing.
Dependent variable: Development of CDI. |
Measurement
Identify primary statistics used to answer clinical questions (You need to list the actual tests done). |
The PRISMA model. | Random effects meta-analysis and pooled prevalence. | Multi-level modelling and meta-regression | Reduction of CDI related to use of Na hypochlorite solution (p <0.5) |
Data Analysis Statistical or
Qualitative findings (You need to enter the actual numbers determined by the statistical tests or qualitative data). |
Handwashing with soap and water associated with low rates of HAIs. | 5.3 CD episodes per 10,000 patient days.CDI mortality = 8.9%. | · 19% of world population washes hands with soap
· Handwashing lowers the risk of contracting diarrheal disease by 40%. |
· 10% Na hypochlorite reduces CD populations in the environment
· Handwashing with chlorhexidine is effective in lowering CDI rates |
Findings and Recommendations
General findings and recommendations of the research |
There was a reduction in the number of those infected with HAIs when hand hygiene was implemented.
Frequent handwashing is recommended for the prevention of HAIs. |
CDI is a HAI with significant mortality risk. | Handwashing with soap and water is effective in reducing diarrheal infections including HAIs.
Routine handwashing is an important public health measure. |
Handwashing with either chlorhexidine or soap and water plus environmental cleaning with Na hypochlorite prevents infections with CD. |
Appraisal and Study Quality
Describe the general worth of this research to practice. What are the strengths and limitations of study? What are the risks associated with implementation of the suggested practices or processes detailed in the research? What is the feasibility of use in your practice? |
He research is important in increasing EBP knowledge.
The strength is that a systematic review provides the highest level of evidence. The limitation is that it is not primary research. Critical Appraisal of Research in Evidence-Based Practice or EBP. There are no risks associated with handwashing. Handwashing is very feasible in the community and healthcare settings. |
The research is important for improvement of clinical practice.
The strength is in the high level of evidence while the weakness is in not being primary research. The risk of antibiotic stewardship is that a deserving patient may be denied antibiotic prescription for fear of resistance. The feasibility of the recommendations is good. They are practical.
|
The study adds to EBP knowledge.
The strength is in the evidentiary value. The limitation is not being primary research. There are no known risks of practicing handwashing. It is highly feasible to apply the findings. |
The study is an important source of EBP information.
It is weak as it has secondary information. The strength is in specificity of recommendations (chlorhexidine and 10% Na hypochlorite). The risks include wrong dilution ratios resulting in corrosion of surfaces and also poisoning from accidental ingestion. The recommendations are feasible. |
Key findings |
Handwashing with soap and water prevents HAIs. | There are significantly high rates of HAIs. | Handwashing reduces infection with diarrheal diseases. | Handwashing and cleaning the environment reduce CDI. |
Outcomes | Reduced rates of HAIs. | Increased rates of CDI mortality. | Lowered rates of diarrheal HAIs. | Low CDI rates. |
General Notes/Comments | The article builds on the knowledge available for evidence-based practice or EBP. | The findings are bound to change clinical practice. | The findings build EBP. | The article enriches EBP. |
Part B: Critical Appraisal of Research Narrative
From the critical appraisal of evidence above, there are several interventions that can be described as best practice that emerge. These practices are evidence-based because they have been tried and tested by way of research. Furthermore, this scholarly research has been peer-reviewed and published in reputed journals. Three of these four studies reviewed are systematic reviews and meta-analyses. In the pyramid of evidence, systematic reviews and meta-analyses provide the highest level of evidence that is needed (level 1) to prove that an intervention is indeed efficacious. For this reason, the following best practice in the form of practice recommendations has the best possible evidence that supports their inclusion into evidence-based practice protocols. The best practice recommendations that emerge are:
References
Andriani, Y., & Nadjib, M. (2018). The importance of implementation of hand hygiene practice in reducing healthcare-associated infections: A systematic review. The 2nd International Conference on Hospital Administration (KnE Life Sciences),135–145. https://doi.org/10.18502/kls.v4i9.3565
Borren, N.Z., Ghadermarzi, S., Hutfless, S., & Ananthakrishnan, A.N. (2017). The emergence of Clostridium difficile infection in Asia: A systematic review and meta-analysis of incidence and impact. PLOS ONE, 12(5), 1-16. https:// doi.org/10.1371/journal.pone.0176797
Freeman, M.C., Stocks, M.E., Cumming, O., Jeandron, A., Higgins, J.P.T., Wolf, J., Prüss-Ustün, A., Bonjour, S., Hunter, P.R., Fewtrell, L., & Curtis, V. (2014). Hygiene and health: Systematic review of handwashing practices worldwide and update of health effects. Tropical Medicine & International Health, 19(8), 906–916. https://doi.org/10.1111/tmi.12339. Critical Appraisal of Research in Evidence-Based Practice or EBP.
Gerding, D.N., Muto, C.A., & Owens Jr, R.C. (2008). Measures to control and prevent Clostridium difficile infection. Clinical Infectious Diseases, 46(Supplement 1), S43-S49. http://dx.doi.org/10.1086/521861
Melnyk, B.M., & Fineout-Overholt, E. (2019). Evidence-based practice in nursing & healthcare: A guide to best practice, 4th ed. Wolters Kluwer.
Use this document to complete the evaluation table requirement of the Module 4 Assessment, Evidence-Based Project, Part 4A: Critical Appraisal of Research
Full APA formatted citation of selected article. | Article #1 | Article #2 | Article #3 | Article #4 |
|
||||
Evidence Level *
(I, II, or III)
|
||||
Conceptual Framework
Describe the theoretical basis for the study (If there is not one mentioned in the article, say that here).**
|
|
|||
Design/Method
Describe the design and how the study was carried out (In detail, including inclusion/exclusion criteria). |
||||
Sample/Setting
The number and characteristics of patients, attrition rate, etc. |
|
|||
Major Variables Studied
List and define dependent and independent variables |
|
|||
Measurement
Identify primary statistics used to answer clinical questions (You need to list the actual tests done). |
||||
Data Analysis Statistical or
Qualitative findings
(You need to enter the actual numbers determined by the statistical tests or qualitative data). |
||||
Findings and Recommendations
General findings and recommendations of the research |
||||
Appraisal and Study Quality
Describe the general worth of this research to practice.
What are the strengths and limitations of study?
What are the risks associated with implementation of the suggested practices or processes detailed in the research?
What is the feasibility of use in your practice? Critical Appraisal of Research in Evidence-Based Practice or EBP. |
||||
Key findings
|
||||
Outcomes
|
||||
General Notes/Comments |
|
*These levels are from the Johns Hopkins Nursing Evidence-Based Practice: Evidence Level and Quality Guide
Experimental, randomized controlled trial (RCT), systematic review RTCs with or without meta-analysis
Quasi-experimental studies, systematic review of a combination of RCTs and quasi-experimental studies, or quasi-experimental studies only, with or without meta-analysis
Nonexperimental, systematic review of RCTs, quasi-experimental with/without meta-analysis, qualitative, qualitative systematic review with/without meta-synthesis
Respected authorities’ opinions, nationally recognized expert committee/consensus panel reports based on scientific evidence
Literature reviews, quality improvement, program evaluation, financial evaluation, case reports, nationally recognized expert(s) opinion based on experiential evidence
ORDER A PLAGIARISM -FREE PAPER NOW
**Note on Conceptual Framework
References
The Johns Hopkins Hospital/Johns Hopkins University (n.d.). Johns Hopkins nursing dvidence-based practice: appendix C: evidence level and quality guide. Retrieved October 23, 2019 from https://www.hopkinsmedicine.org/evidence-based-practice/_docs/appendix_c_evidence_level_quality_guide.pdf
Grant, C., & Osanloo, A. (2014). Understanding, Selecting, and Integrating a Theoretical Framework in Dissertation Research: Creating the Blueprint for Your” House”. Administrative Issues Journal: Education, Practice, and Research, 4(2), 12-26.
Walden University Academic Guides (n.d.). Conceptual & theoretical frameworks overview. Retrieved October 23, 2019 from https://academicguides.waldenu.edu/library/conceptualframework. Critical Appraisal of Research in Evidence-Based Practice or EBP.