Advanced Pharmacology Example Paper

Scenario: A friend calls and asks you to prescribe a medication for her. You have this autonomy, but you don’t have your friend’s medical history. You write the prescription anyway.Advanced Pharmacology Example Paper

Laws: I LIVE in Maryland

Scenario used:

Pharmacokinetic and pharmacodynamic factors altered his or her anticipated response to a drug:

My experiences with hydrochlorothiazide over the last 5 years of my career has been a positive outcome for my patients within the emergency room setting. Anticipated responses to the treatment of hypertension and edema are decreased blood pressure from a hypertensive crisis diagnosis, increased urinary output to eliminate edema and blood pressure parameters are within a safe range. Patients showed improvement with blood pressures and in congestive heart failure patients lungs sounds by elimination of edema. Pharmcodynamics drug movement throughout the body (Rosenthal, L. D., & Burchum, J. R., 2021). It reduces blood volume by acting on the kidneys to reduce sodium (Na+) reabsorption in the distal convoluted tubule.Advanced Pharmacology Example Paper

Consider factors that might have influenced the patient’s pharmacokinetic and pharmacodynamic processes, such as pharmacogenetics: (gender, ethnicity, age, behavior)

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Age: A greater blood pressure reduction and an increase in side effects may be observed in the elderly (i.e., > 65 years) with hydrochlorothiazide. Starting treatment with the lowest available dose of hydrochlorothiazide (12.5 mg) is therefore recommended (fda.gov, n.d.).

Ethnicity: Larger and longer prospective studies are still required to further clarify the long-term safety and metabolic impacts/effects of thiazide diuretics in Nigerians with essential hypertension (Olamoyegun, M., Kolawole, B., & Ajayi, A., 2017).`

Gender: The relationship between the ACE I/D polymorphism and antihypertensive response to a standard dose of HCTZ differs significantly between women and men. Because the D-allele was associated with significant, co-dominant increases in serum ACE activity in both genders, the gender-specific effects of the I/D polymorphism on BP response to HCTZ may be mediated subsequent to the enzymatic generation of angiotensin II (chwartz GL, & Turner ST, et. al., 2002).

Behavior: No information on available at this time.

Think about a personalized plan of care based on these influencing factors and patient history in your case study:Advanced Pharmacology Example Paper

Patient is prescribed Hydrochlorothiazide 12.5 mg p.o daily with a 3 month supply. She will monitor her daily urinary output, weights, pulse rate, blood pressures daily, evaluate edema and keep a record of it. Follow-up appointments every 3 months when refills and new prescription are due. Pt is to report all adverse reactions and side effects as warranted.

Reference:

Rosenthal, L. D., & Burchum, J. R. (2021). Lehne’s pharmacotherapeutics for advanced practice nurses and physician assistants (2nd ed.) St. Louis, MO: Elsevier.

Write a 2- to 3-page paper that addresses the following:

• Explain the ethical and legal implications of the scenario you selected on all stakeholders involved, such as the prescriber, pharmacist, patient, and patient’s family.
• Describe strategies to address disclosure and nondisclosure as identified in the scenario you selected. Be sure to reference laws specific to your state.
• Explain two strategies that you, as an advanced practice nurse, would use to guide your decision making in this scenario, including whether you would disclose your error. Be sure to justify your explanation.
• Explain the process of writing prescriptions, including strategies to minimize medication errors.

To Prepare:

• Review the Resources for this module and consider the legal and ethical implications of prescribing prescription drugs, disclosure, and nondisclosure.Advanced Pharmacology Example Paper
• Review the scenario assigned by your Instructor for this Assignment.
• Search specific laws and standards for prescribing prescription drugs and for addressing medication errors for your state or region, and reflect on these as you review the scenario assigned by your Instructor.
• Consider the ethical and legal implications of the scenario for all stakeholders involved, such as the prescriber, pharmacist, patient, and patient’s family.
• Think about two strategies that you, as an advanced practice nurse, would use to guide your ethically and legally responsible decision-making in this scenario, including whether you would disclose any medication errors.

Resources

Rosenthal, L. D., & Burchum, J. R. (2021). Lehne’s pharmacotherapeutics for advanced practice nurses and physician assistants (2nd ed.) St. Louis, MO: Elsevier.Advanced Pharmacology Example Paper