Alterations in Cellular Process Essay Discussion Paper

The case involves a 27-year-old individual with a substance abuse past. The emergency medical services find the patient sullen after being called by the client’s roommate. Further, the roommate contends that he does not know the duration of time the individual has been lying there. Naloxone is administered in the field, and the male patient becomes receptive. However, he grumbles of a sharp, burning discomfort over his forearm and left hip. Assessment in the emergency department shows a massive amount of necrotic tissue over the forearm and the greater trochanter. Moreover, the EKG shows continual PR interval and peaked T waves. The serum potassium level was 6.9 mEq/L. Alterations in Cellular Process Essay Discussion Paper

The client may be enduring Rhabdomyolysis because of the persistent immobility linked to the perpetual unresponsiveness due to narcotic overdose. This initial diagnosis is founded on the male patient being perfunctory for an unknown period, necrotic tissue, and raised serum potassium. Further, the amalgamated components lead to the breakdown of cells like the sarcolemmal membrane and skeletal muscle tissue. Also, the EKG outcomes are persistent PR interlude and pointed T waves, which are linked to the raised potassium.

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Further, this illness comprises fast cessation of injured skeletal muscle cells because of perpetual immobility. In addition, the unsettling of skeletal muscle unity causes instant discharge of intracellular muscle elements that encompass creatine, myoglobin, lactate, aldolase, kinase, and electrolytes like potassium. Notably, the raised potassium levels are due to injured skeletal muscles discharging the electrolyte. Alterations in Cellular Process Essay Discussion Paper

Even though the role of genetics may be debatable, Ólafsdóttir. (2020) contends that a person’s risk of substance abuse is proportionate to the level of genetic link to an addicted close relative. This means that addiction to alcohol and drugs encompasses many composite elements like genes and environmental factors. For instance, the D2 subtype of dopamine receptors has been researched in instances of genetic susceptibilities. When an individual consumes alcohol or drugs, the human brain generates dopamine, a neurotransmitter responsible for pleasure paths and brain reward. It is linked with motivation and pleasure emotions. Further, the subtype reacts to dopamine’s presence, implying individuals lacking the gene possess a robust compulsion for drugs and alcohol and may consume more massive amounts than those with this gene. Furthermore, in this case, some arguments may contend that genes do not play a significant role. Alterations in Cellular Process Essay Discussion Paper

The male client was unresponsive because of an opiate overdose. Further, he received naloxone administered by the EMS and became responsive. Being an opioid antagonist, the naloxone reverses the impact of overdoses. Further, an overdose and opioids slow breathing may lead to respiratory depression. Remarkably, if administered instantly after the start of the depression, it can reverse the toxicity. It is, however, not advisable to administer high doses of naloxone because it can lead to acute withdrawal syndrome encompassing sweating, vomiting, and tremors (Shaw et al., 2019). Further, massive quantities of necrotic over the forearm and trochanter left hip may be because of the fall when he loses responsiveness. Additionally, necrosis implies cellular death because of a lack of oxygen and blood to the tissue – it may be activated by situations that disrupt blood flow.

My stand would not change even if the patient in the case were female. According to Syse et al. (2019), even though one in four clients cured of severe recreational drug poisoning was female, the gender distinction concerning therapy and clinical state is minute. Also, women portray poorer health than men but do not portray an acute clinical cause than their male counterparts. Alterations in Cellular Process Essay Discussion Paper

References

Ólafsdóttir, J. M. (2020). Addiction within families the impact of substance use disorder on the family system.

Shaw, L. V., Moe, J., Purssell, R., Buxton, J. A., Godwin, J., Doyle-Waters, M. M., … & Hohl, C. M. (2019). Naloxone interventions in opioid overdoses: a systematic review protocol. Systematic reviews, 8(1), 1-9.

Syse, V. L., Brekke, M., Grimsrud, M. M., Persett, P. S., Heyerdahl, F., Hovda, K. E., & Vallersnes, O. M. (2019). Gender differences in acute recreational drug toxicity: a case series from Oslo, Norway. BMC Emergency Medicine, 19(1), 1-8.

Please post an explanation of the disease highlighted in the scenario provided. Include the following in your explanation -role genetics plays in the disease, why the patient is presenting with the specific symptoms described, physiologic response to the stimulus presented in the scenario and why you think this response occurred, the cells that are involved in this process, and how another characteristic like gender or genetics would change your response. Alterations in Cellular Process Essay Discussion Paper

Scenario: A 27-year-old patient with a history of substance abuse is found unresponsive by emergency medical services (EMS) after being called by the patient’s roommate. The roommate states that he does not know how long the patient had been lying there. Patient received naloxone in the field and has become responsive. He complains of burning pain over his left hip and forearm. Evaluation in the ED revealed a large amount of necrotic tissue over the greater trochanter as well as the forearm. EKG demonstrated prolonged PR interval and peaked T waves. Serum potassium level 6.9 mEq/L. Alterations in Cellular Process Essay Discussion Paper