Critical Appraisal of Research on the Prevention of Catheter-Associated Urinary Tract Infections (CAUTI)

Critical Appraisal of Research on the Prevention of Catheter-Associated Urinary Tract Infections (CAUTI)

Realtors rely on detailed property appraisals—conducted using appraisal tools—to assign market values to houses and other properties. These values are then presented to buyers and sellers to set prices and initiate offers. Research appraisal is not that different. The critical appraisal process utilizes formal appraisal tools to assess the results of research to determine value to the context at hand. Evidence-based practitioners often present these findings to make the case for specific courses of action. In this Assignment, you will use an appraisal tool to conduct a critical appraisal of published research. You will then present the results of your efforts. Critical Appraisal of Research on the Prevention of Catheter-Associated Urinary Tract Infections (CAUTI). To Prepare: Reflect on the four peer-reviewed articles you selected in Module 2 and the four systematic reviews (or other filtered high- level evidence) you selected in Module 3. Reflect on the four peer-reviewed articles you selected in Module 2 and analyzed in Module 3. Review and download the Critical Appraisal Tool Worksheet Template provided in the Resources. The Assignment (Evidence-Based Project) Part 3A: Critical Appraisal of Research Conduct a critical appraisal of the four peer-reviewed articles you selected by completing the Evaluation Table within the Critical Appraisal Tool Worksheet Template. Choose a total of four peer- reviewed articles that you selected related to your clinical topic of interest in Module 2 and Module 3. Note: You can choose any combination of articles from Modules 2 and 3 for your Critical Appraisal. For example, you may choose two unfiltered research articles from Module 2 and two filtered research articles (systematic reviews) from Module 3 or one article from Module 2 and three articles from Module 3. You can choose any combination of articles from the prior Module Assignments as long as both modules and types of studies are represented. Part 3B: Critical Appraisal of Research Based on your appraisal, in a 1-2-page critical appraisal, suggest a best practice that emerges from the research you reviewed. Briefly explain the best practice, justifying your proposal with APA citations of the research. Critical Appraisal of Research on the Prevention of Catheter-Associated Urinary Tract Infections (CAUTI) .

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Critical Appraisal of Research on the Prevention of Catheter-Associated Urinary Tract Infections (CAUTI)

Part A: Critical Appraisal of Research Articles Matrix

Full APA formatted citation of selected article. Article #1 Article #2 Article #3 Article #4
Fletcher-Gutowski, S., & Cecil, J. (2019). Is 2-person urinary catheter insertion effective in reducing CAUTI? American Journal of Infection Control, 47, 1508-1509. https://doi.org/10.1016/j.ajic.2019.05.014

 

Hollenbeak, C.S., & Schilling, A.L. (2018). The attributable cost of catheter-associated urinary tract infections in the United States: A systematic review. American Journal of Infection Control, 46, 751-757. https://doi.org/10.1016/j.ajic.2018.01.015 Qin C., de Oliveira, G., Hackett, N., Kim, J.Y.S. (2015). Surgical duration and risk of Urinary Tract Infection: An analysis of 1,452,369 patients using the National Surgical Quality Improvement Program (NSQIP). International Journal of Surgery, 20, 107-112. http://dx.doi.org/10.1016/j.ijsu.2015.05.051 Rimmer, M.P., Henderson, I., Keay, S.D., Khan, K.S., & Al Wattar, B.H. (2020). Early versus delayed urinary catheter removal after hysterectomy: A systematic review and meta-analysis. European Journal of Obstetrics & Gynecology and Reproductive Biology, 247, 55-60. https://doi.org/10.1016/j.ejogrb.2020.01.011

 

Evidence Level *

(I, II, or III)

Level II Level I Level II Level I
Conceptual Framework

Describe the theoretical basis for the study (If there is not one mentioned in the article, say that here).**

There is not one mentioned in the article.

The implied framework is that having one nurse oversee another during a procedure provides a better opportunity for spotting mistakes and identifying deviations from procedure. Critical Appraisal of Research on the Prevention of Catheter-Associated Urinary Tract Infections (CAUTI).

There is not one mentioned in the study.

The implied conceptual framework is that the acuity level of a patient is expected to determine the patient’s response to a CAUTI. This means the one with a high acuity level such as those in the ICU would incur higher costs because of a CAUTI.

There is not one mentioned in the study.

The implicit conceptual framework is that prolonged surgery would encourage colonization of the urinary tract by microbes.

There is not one explicitly mentioned in the article.

The implicit conceptual framework is that leaving an indwelling catheter in-situ after major surgery increases the risk of contracting a CAUTI.

Design/Method

Describe the design and how the study was carried out (In detail, including inclusion/exclusion criteria).

A comparative experimental study using the 4 “Es” of Pronovost.

The 4 “E’s” are Engage, Educate, Execute, and Evaluate.

A Systematic review.

Inclusion criteria: Studies conducted between 2000 and 2017, and use of novel patient-level cost data.

The attributable cost estimates appropriately adjusted for inflation to 2016 U.S. dollars. Used the Consumer Price Index.

Comparative study.

Inclusion criterion: Receipt of a general anesthetic.

The patients, who received a general anesthetic got stratified into quintiles by a calculated z-score for their anesthesia time. This was calculated using the standard deviation and mean of their respective current procedural terminology (CPT) code. An analysis of the Z-score standardized the differences in procedures in anesthesia time. Multivariate regression analysis was used to evaluate the independent association of anesthesia

time with risk of UTI. Multiple sub-analyses were performed to evaluate the robustness of our

results.

Systematic review and meta-analysis.

Inclusion criterion: RCTs.

The authors did this systematic review using a prospectively

registered protocol CDR 42019132213 and reported in accordance

with the PRISMA guidelines.

Sample/Setting

The number and characteristics of

patients, attrition rate, etc.

Sample: All the patients with Foley catheters in quarter 1 and quarter 2.

Setting: The hospital.

Sample: 4 studies.

Setting: Research databases.

Sample: 22,305 patients

Setting: Hospital.

Sample: 10 RCTs ( n= 1,120 women)

Setting: Research databases.

Major Variables Studied

List and define dependent and independent variables

Independent variable: Having an indwelling Foley’s catheter.

Dependent variable: Development of CAUTI.

Independent variable: CAUTI prevention measures.

Dependent variable: Development of CAUTI.

Independent variable: Surgical duration

Dependent variable: Development of CAUTI.

Independent variable: Time of urinary catheter removal after hysterectomy.

Dependent variable: Development of CAUTI.

Measurement

Identify primary statistics used to answer clinical questions (You need to list the actual tests done).

Statistical comparison calculator in the National

Healthcare Safety Network.

The PRISMA protocol. ·         Z-score analysis

·         Sub-analysis

·         Random-effect model

·         Weighted mean differences (WMD)

Data Analysis Statistical or

Qualitative findings

(You need to enter the actual numbers determined by the statistical tests or qualitative data).

Unit A

Pulmonary 0/645 (0) 1/666 (1.50) 0/659 (0) .503

Unit B

Progressive

Care

0/524 (0) 1/732 (1.37) 0/692 (0) .514

Unit C

Progressive care 0/153 (0) 2/327 (6.12) 1/265 (3.77) .747

Unit C

CAUTI rate for patients

using UCIP 0/265 (0) .305

Attributable costs of a CAUTI: $, $1,764, $7,670, $8,398, and $10,197. ·         1.5% developed UTI

·         Increased risk of UTI with longer procedures (OR 1.156).

·         Early removal had a higher risk of re-catheterization (RR 0.42, 95% CI).
Findings and Recommendations

General findings and recommendations of the research

A 2-person insertion protocol using a checklist reduced the incidence of CAUTI.

Two persons should be involved in inserting an in-dwelling catheter to reduce mistakes.

The cost of a CAUTI varies greatly depending on the patient’s status but especially their acuity levels. There is a likelihood of UTI with prolonged surgical procedures.

Attention should be paid to the indwelling catheter during long surgery.

Time of catheter removal matters.
Appraisal and Study Quality

Describe the general worth of this research to practice.

What are the strengths and limitations of study?

What are the risks associated with implementation of the suggested practices or processes detailed in the research?

 

What is the feasibility of use in your practice?

This research is very important for EBP.

The strength is in the fact that it is primary research. The limitation is that it does not have a particular sample size or methodological clarity. This impacts negatively on its validity and reliability.Critical Appraisal of Research on the Prevention of Catheter-Associated Urinary Tract Infections (CAUTI).

The only risk associated with implementing these recommendations is that more staff will be needed for the same procedure, denying other tasks the chance to be completed on time.

The feasibility of implementing the findings is not very high due to the ever-present problem of staff shortage.

This study is crucial for clinical practice decisions on cost.

The strength is that it is a level I evidence study. The limitation is that it is not primary research.

There is no foreseeable risk associated with implementing the findings.

Feasibility of implementation is high.

The study helps EBP development.

The strength is that it is a primary experimental study. The limitation is that it used a convenience sampling technique.

The risk of implementing the findings is that surgeries may be rushed.

Implementation is feasible.

Study helps enrich EBP.

Its strength lies in the fact that it is a systematic review of level I evidence. It however has the limitation of being a filtered study that is not primary research.

The risk is that a catheter may be removed too early when the post-surgery patient still needs it.

Implementation is feasible.

 

Key findings

Two staff performing catheter insertion with one using a checklist prevents CAUTI incidence. The cost of a CAUTI in the inpatient setting varies greatly. Long surgeries predispose to CAUTI. Late catheter removal causes CAUTI
 

Outcomes

Lower CAUTI rates. Rising cost of CAUTI. Increased CAUTI rates with prolonged surgeries. Rise in CAUTI rates
General Notes/Comments The study adds to the EBP knowledge available. The study improves clinical practice. Study builds on EBP knowledge. Builds EBP.

 

 

Part B: Critical Appraisal Narrative for the Four Articles in the Matrix

Scholarly research that is peer-reviewed is what serves as the source for the evidence needed for evidence-based practice (EBP). EBP is best practice as interventions have proven efficacy that is backed by scholarly evidence. The opposite of this would be common practice in which interventions are used just as a matter of course; or just because they have always been used that way (Melnyk & Fineout-Overholt, 2019). Catheter-associated urinary tract infections (CAUTI) are part of a collection of acquired conditions known as hospital-acquired infections (HAIs). They are a significant clinical problem in nursing practice, resulting in unwarranted morbidity and mortality. Critical Appraisal of Research on the Prevention of Catheter-Associated Urinary Tract Infections (CAUTI).Because it is preventable, it is a quality improvement (QI) matter and its rates serve as a quality indicator or benchmark. A plethora of peer-reviewed research exists that provide evidence for a variety of measures that can be taken to prevent the rising rates of CAUTIs in the healthcare setting. The matrix above critically analyzes four of these articles and comes up with the following best practice recommendations:

  1. It is better for two nursing staff to perform the procedure of urinary catheterization together, with one using a checklist to make sure the other colleague follows the steps as required (Fletcher-Gutowski & Cecil, 2019). This safety precaution has been proven to reduce the incidence of CAUTIs.
  2. CAUTIs as infections are costly and increase the cost of hospitalization. A study has found that this cost however varies greatly depending on the patient’s acuity level (Hollenbeak & Schilling, 2018). According to this study, the critical care patient incurs the highest cost for a CAUTI. Reducing this cost should be a priority.
  3. Having prolonged surgery is a predisposing factor for the development of a CAUTI for the patient undergoing a major operation (Qin et al., 2015). This means that microbes take advantage of the latency to colonize the urinary tract. Disinfecting the tract or repeatedly cleaning the meatus during prolonged surgeries would be a critical clinical decision.
  4. Late catheter removal for surgical patients post-surgery causes or predisposes to CAUTI (Rimmer et al., 2020). This was especially true for the hysterectomy patients studied. Indwelling catheters should therefore be removed as early as is feasible.


References

Fletcher-Gutowski, S., & Cecil, J. (2019). Is 2-person urinary catheter insertion effective in reducing CAUTI? American Journal of Infection Control, 47, 1508-1509. Critical Appraisal of Research on the Prevention of Catheter-Associated Urinary Tract Infections (CAUTI). https://doi.org/10.1016/j.ajic.2019.05.014

Hollenbeak, C.S., & Schilling, A.L. (2018). The attributable cost of catheter-associated urinary tract infections in the United States: A systematic review. American Journal of Infection Control, 46, 751-757. https://doi.org/10.1016/j.ajic.2018.01.015

Melnyk, B.M., & Fineout-Overholt, E. (2019). Evidence-based practice in nursing & healthcare: A guide to best practice, 4th ed. Wolters Kluwer.

Qin C., de Oliveira, G., Hackett, N., Kim, J.Y.S. (2015). Surgical duration and risk of Urinary Tract Infection: An analysis of 1,452,369 patients using the National Surgical Quality Improvement Program (NSQIP). International Journal of Surgery, 20, 107-112. http://dx.doi.org/10.1016/j.ijsu.2015.05.051

Rimmer, M.P., Henderson, I., Keay, S.D., Khan, K.S., & Al Wattar, B.H. (2020). Early versus delayed urinary catheter removal after hysterectomy: A systematic review and meta-analysis. European Journal of Obstetrics & Gynecology and Reproductive Biology, 247, 55-60. https://doi.org/10.1016/j.ejogrb.2020.01.011

Evaluation Table

Use this document to complete the evaluation table requirement of the Module 4 Assessment, Evidence-Based Project, Part 4A: Critical Appraisal of Research

 

 

Full APA formatted citation of selected article. Article #1 Article #2 Article #3 Article #4
Qin, C., de Oliveira, G., Hackett, N., & Kim, J. Y. S. (2015). Surgical duration and risk of urinary tract infection: An analysis of 1,452,369 patients using the national surgical quality improvement program (NSQIP). International Journal of Surgery20, 107–112. https://doi-org.ezp.waldenulibrary.org/10.1016/j.ijsu.2015.05.051

 

 

 

 

     
Evidence Level *

(I, II, or III)

 

Level V      
Conceptual Framework

 

Describe the theoretical basis for the study (If there is not one mentioned in the article, say that here).**

 

 

 

 

 

     
Design/Method

 

Describe the design and how the study was carried out (In detail, including inclusion/exclusion criteria).

Patients, who received general anesthesia, were stratified into quintiles by a calculated z-score for their anesthesia time based on the standard deviation and mean of their respective current procedural terminology (CPT) code. Z-score analysis standardized interprocedural differences in anesthesia time. Multivariate regression analysis was employed to evaluate the independent association of anesthesia time with risk of UTI. Multiple sub-analyses were performed to evaluate the robustness of the results.

All patients with pre-operative systemic infection were excluded. Critical Appraisal of Research on the Prevention of Catheter-Associated Urinary Tract Infections (CAUTI).

     
Sample/Setting

 

The number and characteristics of

patients, attrition rate, etc.

 

 

 

 

 

     
Major Variables Studied

 

List and define dependent and independent variables

 

 

     
Measurement

 

Identify primary statistics used to answer clinical questions (You need to list the actual tests done).

       
Data Analysis Statistical or

Qualitative findings

 

(You need to enter the actual numbers determined by the statistical tests or qualitative data).

       
Findings and Recommendations

 

General findings and recommendations of the research

       
Appraisal and Study Quality

 

 

Describe the general worth of this research to practice.

 

What are the strengths and limitations of study?

 

What are the risks associated with implementation of the suggested practices or processes detailed in the research?

 

What is the feasibility of use in your practice? Critical Appraisal of Research on the Prevention of Catheter-Associated Urinary Tract Infections (CAUTI).

       
 

 

Key findings

 

 

 

       
 

 

Outcomes

 

 

 

       
General Notes/Comments  

 

 

 

 

 

     

 

*These levels are from the Johns Hopkins Nursing Evidence-Based Practice: Evidence Level and Quality Guide 

  • Level I

Experimental, randomized controlled trial (RCT), systematic review RTCs with or without meta-analysis

 

  • Level II

Quasi-experimental studies, systematic review of a combination of RCTs and quasi-experimental studies, or quasi-experimental studies only, with or without meta-analysis

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  • Level III

Nonexperimental, systematic review of RCTs, quasi-experimental with/without meta-analysis, qualitative, qualitative systematic review with/without meta-synthesis

  • Level IV

Respected authorities’ opinions, nationally recognized expert committee/consensus panel reports based on scientific evidence

  • Level V

Literature reviews, quality improvement, program evaluation, financial evaluation, case reports, nationally recognized expert(s) opinion based on experiential evidence

**Note on Conceptual Framework

  • The following information is from Walden academic guides which helps explain conceptual frameworks and the reasons they are used in research.Critical Appraisal of Research on the Prevention of Catheter-Associated Urinary Tract Infections (CAUTI).  Here is the link https://academicguides.waldenu.edu/library/conceptualframework
  • Researchers create theoretical and conceptual frameworks that include a philosophical and methodological model to help design their work. A formal theory provides context for the outcome of the events conducted in the research. The data collection and analysis are also based on the theoretical and conceptual framework.
  • As stated by Grant and Osanloo (2014), “Without a theoretical framework, the structure and vision for a study is unclear, much like a house that cannot be constructed without a blueprint. By contrast, a research plan that contains a theoretical framework allows the dissertation study to be strong and structured with an organized flow from one chapter to the next.” Critical Appraisal of Research on the Prevention of Catheter-Associated Urinary Tract Infections (CAUTI).
  • Theoretical and conceptual frameworks provide evidence of academic standards and procedure. They also offer an explanation of why the study is pertinent and how the researcher expects to fill the gap in the literature.
  • Literature does not always clearly delineate between a theoretical or conceptual framework. With that being said, there are slight differences between the two.

References

The Johns Hopkins Hospital/Johns Hopkins University (n.d.). Johns Hopkins nursing dvidence-based practice: appendix C: evidence level and quality guide. Retrieved October 23, 2019 from https://www.hopkinsmedicine.org/evidence-based-practice/_docs/appendix_c_evidence_level_quality_guide.pdf

Grant, C., & Osanloo, A. (2014). Understanding, Selecting, and Integrating a Theoretical Framework in Dissertation Research: Creating the Blueprint for Your” House”. Administrative Issues Journal: Education, Practice, and Research, 4(2), 12-26.

Walden University Academic Guides (n.d.). Conceptual & theoretical frameworks overview. Retrieved October 23, 2019 from https://academicguides.waldenu.edu/library/conceptualframework. Critical Appraisal of Research on the Prevention of Catheter-Associated Urinary Tract Infections (CAUTI).