Cytochrome P450 System Assignment
Directions
Pharmacokinetic actions are mediated through the hepatic and gut drug-metabolizing system known as the cytochrome P540 (CYP) enzyme system. Select medications that you would likely prescribe or encounter frequently in your practice (ideally psychopharmaceutical agents).
Please answer the following questions, assigned by the first letter of your last name. Include at least two references other than Stahl in your answers. Also, please write two test questions covering the information in your initial post.
1. I–O: Please state what the CYP 2D6 enzyme is, why it is important, and what it does in the body. List common medications, foods, herbs, and/or substances that inhibit this enzyme, including any substrates, and any important medication restrictions regarding this enzyme.
Post your original response by the end of Day 3. Then, by the end of Day 6, respond to at least one of your classmates’ posts for each of the other two enzymes (responding to two classmates altogether), including answering their test questions.
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Maryville Standard Discussion Board Rubric B
| Maryville Standard Discussion Board Rubric B |
| Criteria |
Ratings |
Pts |
| This criterion is linked to a Learning OutcomeInitial Post: Relevance to the Topic of Discussion |
| 6.0 pts
The posting directly addresses key issues, questions, or problems related to the topic of discussion. The posting applies course concepts with examples showing applied knowledge and understanding of topic with appropriate use of at least two citations/references. Post has been submitted by the due date. (6 points) Cytochrome P450 System Assignment
|
5.0 pts
The posting has not fully addressed the question(s) or problems related to the topic. And/or no citations/references are used. And/or initial posting is not submitted by the due date. (3-5 points) |
2.0 pts
The posting does not directly address the question or problem posed by the discussion and/or no initial discussion post will result in a zero. (0-2 points) |
|
6.0 pts |
| This criterion is linked to a Learning OutcomeInitial Post: Insight and Application of Course Concepts |
| 6.0 pts
The posting offers original and thoughtful insight, synthesis, or observation that demonstrates a strong understanding of the concepts and ideas pertaining to the discussion topic (use of examples). Use at least two appropriate citations/references to support all claims and facts. (6 points) |
5.0 pts
The posting presents minimal insight, analysis, or observation to the topic presentation (no examples of applicability or detailed discussion). Appropriate use of citations/references to support presenting ideas. And/or no use of citations/references. (3-5 points) |
2.0 pts
The posting does not offer any significant insight, analysis, or observation related to the discussion topic. And/or no initial discussion post will result in a zero. (0-2 points) |
|
6.0 pts |
| This criterion is linked to a Learning OutcomePeer Responses: Number of Responses |
| 4.0 pts
Two peer responses are provided with at least one peer response that has a citation/reference; each posted on a different day from each other and from the initial posting. (4 points) |
3.0 pts
Minimum number of responses is not posted and/or no citation/reference is used and/or all postings are made on the same day. (1-3 points) Cytochrome P450 System Assignment
|
0.0 pts
No peer responses are posted and/or responses are posted after the due date. (0 points) |
|
4.0 pts |
| This criterion is linked to a Learning OutcomePeer Responses: Quality of Response Posts |
| 4.0 pts
The response is a substantive interaction that builds on the discussion question and ideas of others while using course content with appropriate citation/references. Post is made by the due date. (4 points) |
3.0 pts
The response is somewhat substantive and includes appropriate citations/references and/or no citation/reference is used. (1-3 points) |
0.0 pts
The response is not substantive and does not build on the ideas from weekly objectives and required readings, nor does it include a citation/reference. Or no response to peer by due date. (0 points) |
|
4.0 pts |
| Total Points: 20.0 |
Cytochrome P450 System Assignment
