NUR 641E WK8 DQ1 Assignment

Vasopressin, also called the antidiuretic hormone ADH, is a hormone that is secreted in reaction to decreased blood pressure. When plasma osmotic concentration rises or blood volume falls, the signals are conveyed to the hypothalamus to start making ADH. Released by the pituitary gland, the function of ADH is to boost the permeability of distal renal tubular cells to water, improve the absorption of water, and promote the restoration of plasma blood pressure and volume (McCance & Huether, 2019). Individuals experiencing shock due to hypovolemia or sepsis are at higher risk of deficiency of tissue perfusion and respiration that may cause cellular ischemia. This disorder is associated with a death rate as high as 50% (Curry et al., 2015). NUR 641E WK8 DQ1 Assignment

In the initial stages of shock, the production and secretion of vasopressin can be as large as 200 times the standard release (Deutschman & Neligan, 2019). Worse shock ultimately contributes to reduced vasopressin production and decreased peripheral vasopressin receptor capacity. The final stage of shock will exhaust the availability of vasopressin, making patients ferritic to catecholamine therapy and volume intubation (Sims, Guan, & Bergey, 2017). Dependent on serum vasopressin amounts, the disorder may be classified as an absolute deficiency or relative deficiency.NUR 641E WK8 DQ1 Assignment

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The clinical manifestation of these cases is the same as that of most shock victims. Hemodynamic dysfunction is the main concern since these patients are highly hypotensive and exhibit signs of reduced end-organ perfusion including decreased urinary production, impaired mental state, and hypoxia. If not changed, these patients would need elevated measures of treatment for blood pressure and oxygenation. Patients that are hemodynamically unhealthy may undergo advanced screening.

These individuals are chronically sick and information in this disorder is not sufficient for the patient. Training will be family-centered and entail educating the patient about the disease mechanism and any treatments that could be pursued. I would teach the family about the state of the patient and all the medications that are provided. It should also be remembered that education is not and cannot be performed until the patient has recovered.

References

Curry, N., Hopewell, S., Doree, C., Hyde, C., Brohi, K., and Stantworth, S. (2015). The acute management of trauma hemorrhage: a systematic review of randomized control trials. Critical Care 15;2.

Deutschman, C. & Neligan, P. (2019). Evidence-based practice of critical care. St. Louis, MO: Elsevier Inc.

McCance, K. L., & Huether, S. E. (2019). Pathophysiology: the biologic basis for disease in adults and children. St. Louis, MO: Elsevier Inc.

Sims, C., Guan, Y., & Bergey, M. (2017). Arginine vasopressin, copeptin, and the development of relative AVP deficiency in hemorrhagic shock. American Journal of Surgery, 214(4): 589-595.  NUR 641E WK8 DQ1 Assignment