Pharmacology And Toxicology Discussion Essay

Advanced Pharmacology

At the hospital recently, there was a case involving a gentleman who was 80 years old and had a medical background. He came to the emergency room with complaints of pain in his hip and shoulder after being involved in a car accident. It is worth noting that he has a history of blood pressure, diabetes, chronic back pain and struggles with alcohol abuse. The providers observed that his emotional wellbeing seemed affected by the loss of his wife to breast cancer. Although he denied using tobacco or drugs, he did admit to consuming a pint of whiskey every day for the six months. The patient’s presentation was complicated by an elevated blood alcohol level (0.10) at the time of assessment. X-rays revealed a right acetabulum and right clavicle fracture sustained when he walked away from the accident scene. Pharmacology And Toxicology Discussion Essay

Several factors could influence the pharmacokinetic and pharmacodynamic processes in this patient. According to Ștefănescu et al. (2020), changes in liver function that occur with age could impact how the body metabolizes alcohol and clears medications. Furthermore, the patients long term alcohol abuse might activate liver enzymes potentially altering how drugs are processed in the body (Zeng et al., 2020). Since the patient’s kidney function may be reduced due to their age it may be necessary to adjust the dosage of medications that are eliminated through the kidneys. It is important to take into account any interactions, between medications and alcohol. Pharmacology And Toxicology Discussion Essay

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To ensure the care for this patient there is need to adopt an approach that involves multiple disciplines. Given his pain history and the fractures from the accident it is crucial to prioritize pain management. However, healthcare professionals in charge must exercise caution due to interactions between pain medications and alcohol (Ștefănescu et al., 2020). Considering his struggles with depression and insomnia, it would be beneficial to involve a consultant in order to address his emotional wellbeing. To tackle his alcohol abuse it is important to incorporate interventions such as counseling and support groups focused on alcohol cessation into the treatment plan. Considering his age-related changes and compromised liver function it may be necessary to administer medication doses while closely monitoring any potential adverse effects. Ultimately tailoring the treatment plan by taking into account the patient’s history, emotional wellbeing and pharmacological considerations is essential for promoting wellness and facilitating recovery. Pharmacology And Toxicology Discussion Essay

References

Ștefănescu, R., Tero-Vescan, A., Negroiu, A., Aurică, E., & Vari, C. E. (2020). A comprehensive review of the phytochemical, pharmacological, and toxicological properties of Tribulus terrestris L. Biomolecules, 10(5), 752.

Zeng, X., Guo, F., & Ouyang, D. (2020). A review of the pharmacology and toxicology of aucubin. Fitoterapia, 140, 104443.

Case Study
80 year old man with a medical history of high blood pressure, diabetes, chronic back pain and etoh abuse, presented to ER level one c/o right hip pain and right shoulder pain after having a MV Accident 24 hours after intoxication. He has experienced increasingly isolated behaviors after his wife dying from breast cancer 6 months ago. He states life has changed for him since the death of his spouse of 40 years. Denies any present tobacco or drug use but drinks a pint of whisky a day for the last 6 months. He also complained of insomnia and depression. After a complete workup in the ER, labs noted patient had an elevated etoh level of 0.10, X ray of the hip showed a right acetabulum fracture and a right clavicle fracture. He walked away from his car after hitting a tree because he did not want to get arrested. Pharmacology And Toxicology Discussion Essay

Post a description of the patient case from your experiences, observations, and/or clinical practice from the last 5 years. Then, describe factors that might have influenced pharmacokinetic and pharmacodynamic processes of the patient you identified. Finally, explain details of the personalized plan of care that you would develop based on influencing factors and patient history in your case. Be specific and provide examples. Pharmacology And Toxicology Discussion Essay